15-16 November 2019

Catherine Robb

Research Assistant / Imperial College London
Speaker Resdem 2019

Catherine Robb is a PhD student and Research Assistant at Imperial College London; Neuroepidemiology and Ageing Research Unit. Her research is primarily exploring the role of physical activity in maintaining cognitive health in older age. More specifically, she is evaluating how physical activity interacts with established genetic, imaging and fluid biomarkers of Alzheimer’s disease in reducing likelihood of cognitive decline and eventual dementia.

She is conducting a deeper investigation of the underlying biomechanisms associated with these processes including the exploration of certain neurotrophic factors and molecular pathways. Coming from a psychological background, Catherine initially joined the department as an assistant psychologist supporting the coordinating of a large cohort observational study exploring early indicators of dementia and identifying sensitive cognitive assessments for detection of the earliest stage of cognitive decline.

Enrico Premi

Clinical neurologist / University of Brescia (Italy)
Speaker Resdem 2019

Dr. Premi attended medical school at the University of Brescia (Italy) and completed his residency program in Neurology at University of Brescia (Prof. Padovani) in 2012. He currently has a permanent contract as clinical neurologist in the Stroke Unit, ASST “Spedali Civili” (Brescia, Italy), continuing his research activity in collaboration with the  Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia.

Since his residency period Dr. Premi’s research interests concern neurodegenerative diseases, in particular Frontotemporal Dementia (FTD) taking advantage of advanced neuroimaging techniques to explore structural and functional correlates of the disease. In the last five years he focused on the preclinical phase of FTD (studying presymptomatic carriers of FTD causative mutations) as well as on neuroanatomical correlates of Cognitive Reserve in FTD.

Arfan Ikram

Professor and chair of Epidemiology / Erasmus MC Rotterdam
Speaker Resdem 2019

Dr. Ikram am professor and chair of Epidemiology at the Erasmus MC Rotterdam, the Netherlands. He is also adjunct professor of Epidemiology at the Harvard Chan School of Public Health.

Dr. Ikram is principal investigator of the Rotterdam Study and also lead the neuro-core in the Rotterdam Study. He is also a key collaborator in the CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) consortium. His research focuses on investigating the etiology of neurologic diseases in the elderly, with a particular focus on dementia, Alzheimer disease, stroke, and Parkinson disease. The main areas of research are to elucidate the earliest signs of brain diseases, before clinical symptoms are present, and to understand how these lead to clinical manifestation of disease. Moreover, he is interested in preclinical signs that can be used to identify persons at highest risk of developing disease. To this aim he has used data from the large population-based Rotterdam Study and Rotterdam Scan Study that have followed nearly 15,000 persons for a period of nearly 25 years. A main focus on his research has been the use of MRI-imaging to understand brain disease. Also, he has used neuropsychological testing, genome-wide, exome chip, DNA-methylation and sequencing technologies, and recently electronic gait assessments. Not only is he interested in how these pre-clinical markers lead to clinical disease, he also wants to disentangle the intricate relationships between these markers.

Dr. Ikram has published over 380 international scientific papers (H-index = 49) and currently head a research group of 13 PhD-students, 3 post-docs, 3 MSc-students, and 5 research staff.

Eider Arenaza-Urquijo

Postdoctoral researcher / Institute of Health and Medical Research (INSERM, Caen, France)
Speaker Resdem 2019

Dr. Eider Arenaza-Urquijo is a senior postdoctoral researcher at the French National Institute of Health and Medical Research (INSERM, Caen, France). She obtained her PhD degree at the University of Barcelona (Catalonia, Spain) and conducted a research stay at the University of California, Berkeley (California, US).

The central focus of her research work is to understand the neural underpinnings of normal cognition in the setting of Alzheimer’s disease pathology. Her research notably focuses on how lifestyle factors (e.g., cognitive and physical activities) influence brain structure and function, associate with Alzheimer’s disease pathological processes and interact with genetic risk.

 


 

Yaakov Stern

Professor of Neuropsychology / Columbia University College
Speaker Resdem 2019

Yaakov Stern is Professor of Neuropsychology in the Departments of Neurology and Psychiatry, as well as the Taub Institute for the Research on Alzheimer’s Disease and the Aging Brain, at Columbia University College of Physicians and Surgeons.  He is chief of the Cognitive Neuroscience Division of the Department of Neurology.

Dr. Stern’s research focuses on cognition in normal aging and in diseases of aging, particularly Alzheimer’s disease.  One strong focus of his current research program is investigating the neural basis of cognitive reserve.  He is also conducting a large scale imaging study to identify unique neural networks underlying the major cognitive abilities affected by aging, and a study developing models to predict the clinical course of Alzheimer’s disease.

Dr. Stern’s research approach includes classic neuropsychological and cognitive experimental techniques, with a strong focus on neuroimaging.  He has published over 550 peer-reviewed papers, numerous chapters, and edited a book on cognitive reserve.

Robert Perneczky

Professor and Head of Geriatric Psychiatry / University of Munich
Speaker Resdem 2019

Robert Perneczky conducts dementia prevention research at the University of Munich and Imperial College London. His studies apply a range of methodologies to advance the understanding of biological and clinical processes that lead to cognitive decline and associated disability. This includes imaging, fluid biomarker, genomics and cognitive assessments in clinical and epidemiological contexts. The concept of cognitive reserve has always been in the centre of Robert’s scientific activities, because of the great relevance for reducing dementia risk in the population and strengthening vulnerable individuals’ resilience against neurodegeneration.

Robert is Professor and Head of Geriatric Psychiatry and Director of the Alzheimer’s Memorial Center at the University of Munich, and he leads several large dementia studies and initiatives in Germany and the UK.

Amos D. Korczyn

Chairman of the Scientific Medical Board / Israeli Alzheimer’s disease association (EMDA)
Speaker Resdem 2019

Professor Korczyn graduated from the Hebrew University–Hadassah Medical School in Jerusalem in 1966 (MD), where he also received an MSc degree in pharmacology (cum laude) in 1966. He trained in neurology at Beilinson Hospital and at the National Hospital for Nervous Diseases, Queen Square, London. He was the Chairman of the Department of Neurology at the Tel-Aviv Medical Center from 1981 until 2002, and the incumbent of the Sieratzki Chair of Neurology at Tel-Aviv University, 1995-2010. Professor Korczyn has a particular interest in neurodegenerative diseases. He has authored or co-authored over 600 articles in peer-reviewed journals, as well as many chapters in books. He edited several books and Special Issues in Journals, and is Regional Editor of the Journal of Alzheimer’s Disease. He is or has been an Editorial Board member of 20 international journals, and organized several neurological conferences, mainly in the field of dementia, Parkinson’s disease and other degenerative brain disorders, as well as CONy – the International Congress on Controversies in Neurology, and has organized the Mental Dysfunction in Parkinson’s disease congresses since 1993. Professor Korczyn served on advisory boards in several drug discovery programs.

Professor Korczyn is the Chairman of the Scientific Medical Board of the Israeli Alzheimer’s disease association (EMDA), member of the SAB of Alzheimer Disease International (ADI), and has been the chairman of the WFN Research Committee for Clinical Neuropharmacology.

Professor Korczyn is an honorary member of the neurological societies of Israel, Serbia, Poland and Russia. Professor Korczyn’s H-index is 63.

Gerd Kempermann

Professor / Center for Regenerative Therapies Dresden (CRTD)
Speaker Resdem 2019

Gerd Kempermann, born in 1965, studied Medicine in Cologne and Freiburg, Germany. From 1995 to 1998 he was postdoctoral fellow with Fred H. Gage at the Salk Institute and between 2000 and 2007 group leader at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch.

Since 2007 he is Professor at the CRTD – Center for Regenerative Therapies Dresden. Since 2009 he is also speaker of the German Center for Neurodegenerative Disease (DZNE) Dresden. Main topics of his work are the function and activity-dependent regulation of adult hippocampal neurogenesis and how both interact in health and disease.

Michael Ewers

Professor / Ludwig-Maximilian-Universität München (LMU)
Speaker Resdem 2019

Michael Ewers’ research focuses on neuroimaging-assessed brain changes in Alzheimer’s disease, based at the Institute for Stroke and Dementia Research (ISD). The major research interest is to understand structural and functional network changes that accelerate or delay the onset of dementia symptoms. For reserve, a major approach is to use graph theoretical analysis to both resting state and task-based MRI in order to identify functional brain changes that underlie higher resilience of cognitive abilities during the course of Alzheimer’s disease. The identification of such protective brain mechanism are sought to be targeted by therapeutic intervention in secondary prevention of Alzheimer’s disease.

Michael is a professor at the Ludwig-Maximilian-University Munich (LMU) since 2012, after research stays at Trinity College Dublin, Ireland and University of California at San Francisco (USCF), USA.