Programme

DAY 1 (Friday, 15th November 2019)

09.20-09.50

Opening ceremony
Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

09.50-10.20

Opening presentation: Opportunities and challenges of reserve research
· Yaakov Stern, Columbia University New York 

 

Chair: Arfan Ikram, Erasmus Medical Centre Rotterdam

10.20-10.40

Genetic association studies of reserve factors
Arfan Ikram, Erasmus Medical Center Rotterdam

10.40-11.00

Brain metabolism and cognitive reserve
Matteo Bauckneht, University of Genoa

11.00-11.20

Left prefrontal cortex and brain functional network efficiency
Nicolai Franzmeier, LMU Munich

11.20-11.40

Dynamic connectivity changes in preclinical frontotemporal dementia
Enrico Premi, University of Brescia

11.40-12.00

MRI connectivity changes in autosomal-dominant Alzheimer’s disease  
Michael Ewers, LMU Munich

12.00-13.00

Lunch break

Chair: Jochen Herms, LMU Munich

13.00-13.20

Altered neurogenesis in Alzheimer’s mouse models
Carla Torrent, University of Barcelona

13.20-13.40

BACE1 inhibition and dendritic spinesJochen Herms, LMU Munich

13.40-14.00

A deposition and microglial response in Alzheimer’s mouse models
Matthias Brendel, LMU Munich

14.00-14.20

Folding mechanisms of alpha-synuclein in vivo Tim Bartels, University College London

14.20-14.40

ADAM10 and synapse function
Stefan Lichtenthaler, TU Munich

14.40-15.55

Coffee break and poster session

Chair: Robert Perneczky, LMU Munich

15.55-17.25

Selected presentations, 15 minutes each

Chair: Michael Ewers, LMU Munich

17.25-17.40

Pro: Appropriate animal models are available
Gerd Kempermann, DZNE Dresden

17.40-17.55

Con: Better animal models must be developed
Amos Korczyn, Tel Aviv University

17.55-18.10

Discussion and rebuttals

DAY 2 (Saturday, 16th November 2019)

08.30-08.35

Welcome
Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

08.35-09.05

Special lecture: The antimicrobial protection hypothesis of Alzheimer's disease
 

Chair: Hans-Jürgen Möller, LMU Munich

09.05-09.25

Clinical aspects of neuroinflammation in Alzheimer’s disease
Norbert Müller, Marion v. Tessin Center 

09.25-09.45

In vivo imaging of glial activation
Magdalena Sastre, Imperial College London 

09.45-10.05

Inflammasome signalling in neurodegenerative disorders
Michael Heneka, University of Bonn

10.05-10.25

Astroglial imaging in early Alzheimer’s disease
Paul Edison, Imperial College London

10.25-10.45

Neuroinflammation in Alzheimer’s disease: the ActiGliA study
Robert Perneczky, LMU Munich

10.45-11.10

Coffee break

Chair: Cecilia Samieri, University of Bordeaux

11.10-11.30

The contribution of mid-life activities to late-life cognitive reserve
Dennis Chan, University of Cambridge

11.30-11.50

Functional and structural connectivity changes and their association with lifestyle factors in the DELCODE study
Boris-Stephan Rauchmann, LMU Munich

11.50-12.10

Cardiovascular health and dementia risk
Cecilia Samieri, University of Bordeaux

12.10-12.30

Physical activity, apolipoprotein-ɛ4 and multi-domain cognition among healthy older adults
Catherine Robb, Imperial College London

12.30-12.50

Sleep disturbance and dementia risk​​​​​​​
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Shireen Sindi, Karolinska Institute Stockholm

12.50-14.00

Lunch break

Chair: Alina Solomon, University of Eastern Finland

14.00-14.20

Biomarkers and response to a multi-modal lifestyle intervention: The FINGER study
Alina Solomon, University of Eastern Finland

14.20-14.40

Challenging neural plasticity in schizophrenia
Alkomiet Hasan, LMU Munich

14.40-15.00

The metabolic brain signature of cognitive resilience
Eider Arenaza-Urquijo, INSERM U1077 Caen 

15.00-15.20

Effects of a 3-Year Multi-Domain Intervention on cognitive performance in older adults with increased dementia risk
Pierre-Jean Ousset, University of Toulouse

15.20-15.40

PET imaging in anti-amyloid treatment trials
Timo Grimmer, TU Munich

15.40-16.00

Closing words and awards presentation
Robert Perneczky, Norbert Müller, LMU Munich / Marion v. Tessin Center

16.00-16.45

Farewell coffee